My ram is high when I start my computer, but nothing is running?

Hi, my RAM on my computer is really high with 4gb available ram and looking at the windows gadget 50-80% of ram is being used, this has jumped significantly recently and programs are now suddenly not responding all the time. Can someone help me please.
new things that have happend to my computer are not much except installing a new graphics tablet.
I have done multiple scans but nothing shows.

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